Hi there,
You've probably heard of DMT - the ‘spirit molecule’- the compound in ayahuasca known for its kaleidoscopic worlds and encounters with aliens and entities.
Far fewer people know its close chemical cousin, 5-MeO-DMT. Which is curious, because by many accounts it is the more incredible of the two.
Found in the venom of the Sonoran Desert toad and in a handful of Amazonian plants, 5-MeO acts on different receptors and does something almost opposite to classic DMT. Where DMT floods you with vision, 5-MeO empties the screen. No imagery. No entities. Often no "you" at all - just the complete dissolution of the self into what people can only describe afterwards as boundless unity, or oneness, or contact with something sacred. It has earned its own nickname: the God molecule.
It is one of the most powerful known psychedelics - and, despite a recent surge of interest, one of the least understood in either science or public conversation. We still know remarkably little about how it works, who it helps, and how to approach it safely. What research does exist points to something striking: it reliably brings on a complete mystical experience - the unitive, boundary-dissolving kind that people routinely rank among the most meaningful moments of their entire lives.
And that's important. Because the thing 5-MeO points to - the quiet, the loss of self-importance, the sense of belonging to something far larger than yourself - is precisely what our optimise-everything culture has no idea what to do with. The contemplative traditions always said it plainly: learn to let go of the self, and you remember how to live.
If you're curious to go deeper, Dr. Alan Davis - who led some of the first research into the effects and safety of 5-MeO-DMT - joins us online this Sunday 31st May (7pm BST) to separate the myth from the science; details and tickets here 👇
At the bottom of this email you will also find:
- 10% off the transformative Entheogenesis psilocybin retreat centre in the Netherlands
- Want to get in on the hottest conversations in psychedelics? Tickets to ICPR - Europe's premier conference for psychedelic research June 4-6th
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FROM OUR PARTNERS
We are delighted to be partnering with the transformative Entheogenesis retreat centre in the Netherlands to offer unique legal psilocybin ceremonies, supported by comprehensive preparation and integration guidance for a safer and deeper experience.
Their approach builds a bridge between ancient plant medicine traditions and modern science-based practices. Curated by a team of experienced trauma-informed guides.
Just leave the code "AWORLDAPPEARS" in the comment section of the application form to get 10% off
The premier psychedelic research conference in Europe
Want to get in on the hottest conversations in psychedelics? ICPR is where science, practice, and policy meet. This is where you'll find intellectual rigour, cutting-edge evidence, and meaningful discussions on the real-world applications of psychedelics. With a strong focus on quality and integrity, ICPR is not about hype; it's about knowledge, impact, and the future of the field.
Join our community of members!
We fund our work in community-building and psychedelic education primarily through our membership program.
By becoming a member of The Psychedelic Society community, you get access to exclusive members-only events, a discount on events, and support the development of this alternative cultural space. Membership starts from just £5/month!
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