In recent weeks, Bryan Johnson livestreamed a high-dose 5-MeO-DMT experience to hundreds of thousands of viewers - bringing one of the most powerful psychedelics into the mainstream spotlight.

The broadcast has sparked widespread curiosity, debate, and concern. From bold claims around longevity and “brain resets,” to questions about safety, dosing, and public influence, it raises an urgent question:

What happens when something this intense, personal, and poorly understood goes viral?

This rapid-response panel, hosted by the Psychedelic Society, brings together leading voices across research, therapy, and harm reduction to unpack the moment and provide grounded, evidence-informed perspectives.

What we’ll explore

• What 5-MeO-DMT is—and how it differs from other psychedelics
• How Johnson’s 27mg protocol compares to clinical research
• The risks associated with high-dose use
• Why “set and setting” and expectation matter
• The role of preparation and integration
• Psychedelics and longevity: what does the science actually say?
• The cultural shift toward psychedelics as optimisation tools
• What responsible engagement with these substances really looks like

Why attend?

As psychedelics continue to move into the mainstream, conversations are happening faster than the science can keep up. This event offers a chance to step back from the hype and hear from professionals working directly in the field.

Whether you’re a clinician, researcher, or simply curious, this panel aims to provide clarity, context, and critical insight into one of the most talked-about moments in psychedelics this year.

Can’t attend the live event? No problem — all ticket holders will get access to the recording.

SPEAKERS

Hattie Wells

Hattie Wells is a psychedelic facilitator and co-director of Breaking Convention, bringing over twenty years of experience as a practitioner, researcher, and consultant in the field. Her clinical work spans multiple trials, with her most sustained collaboration being with Beckley Psytech, where she has worked as a session facilitator, advisor, and psychological support lead on their 5-MeO-DMT research for treatment-resistant depression. She also carries out harm reduction work with PsyAware and facilitates psilocybin retreats with Alalaho.

Timmy Davis

Timmy Davis is director of psychedelic policy and regulation at the Centre for Evidence Based Drug Policy (CEBDP), co-founder and policy director at the Psilocybin Access Rights (PAR) campaign, the founder of The Psychedelic Experience Clinic and a trainee at the Site for Contemporary Psychoanalysis.

Anya Ragnhildstveit

Anya Ragnhildstveit is a Clinical Research Scientist and PhD Candidate in Psychiatry at the University of Cambridge, where she is part of the Cambridge Psychedelic Research Group (CPRG). Her work focuses on the safety and therapeutic potential of dissociatives, empathogens, and classic psychedelics for severe mental illness. She also serves as a psychedelic facilitator for industry-sponsored clinical trials at Inner Space Research. Anya is the Founder and CEO of Pneuma Science, an international research organisation exploring plant medicines and next-generation neuroplastogens to support mental health and human flourishing. She has a particular research focus on 5-MeO-DMT, including publishing the first case study on its use for chronic PTSD and leading an observational study of 5-MeO-DMT-assisted Internal Family Systems (IFS) therapy. Alongside her research, Anya is active in psychedelic policy in the United States. She first-authored a major technical report under Texas House Bill 1802 and, more recently, served as Lead Scientific Policy Advisor on Utah House Bill 390, supporting the development of a state-led clinical trial of 5-MeO-DMT-assisted therapy for veterans with treatment-resistant PTSD.

Otto Maier

Otto is known in the psychedelic Industry for his approach to psychedelic Integration and his work directly supporting some of the more intense psychedelic crisis cases in his private practice "Soul & Psyche". Trained in depth psychology, somatic experiencing, Internal Family Systems, and an intention to decolonize the psyche. With a rich history working in the psychedelic industry as a long time retreat leader for Tandava Retreats and Lead Trainer for FIVE, teaching medical professionals and therapists the art of comprehensive psychedelic work with 5 meo. He accompanies those moving through spiritual crisis, psychedelic processes, and experiences that exceed the language of ordinary life through holding space for a deeper experience of the soul and psyche. 

HOST

Ryan Khan

Ryan is the Online Events Coordinator for The Psychedelic Society and a life-long psychedelic enthusiast. He is completing his MSc in Psychedelics: Mind, Medicine & Culture at The University of Exeter where he specialises in the extra-pharmacological factors affecting psychedelic assisted therapy. Ryan also sits at the intersection of psychedelic research, education and therapy. He works as a Research Assistant at Pneuma Science, Consultant at Psilonautica and Trip Sitter at Beautiful Space. Follow Ryan on LinkedIn.

REFUNDS POLICY: Please note, we do not arrange refunds or exchanges. When possible we encourage reselling on Ticketswap.

ACCESS:  We do our best to include everyone in our events, regardless of health circumstances. If you have access requirements please email the event organiser directly to discuss. Many facilitators are able to offer reduced ticket prices for those truly unable to afford the ticket price. If this applies to you, do please get in touch with the event organiser.

For PSYCHEDELIC KNOWLEDGE AND RESOURCES please check out the Psychedelic Society website. 

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